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When does Grey's Anatomy Season 4 come out?

Grey's Anatomy Season 4 premiered Thursday, September 27, 2007 on ABC and ended Thursday, May 22, 2008. The season has 17 episodes.

Enter a world of change in the irresistible and unforgettable fourth season of Grey's Anatomy. Love, lies, and family ties are revealed as the surgeons of Seattle Grace discover that their choices have major unintended consequences. And coupled with the arrival of some very eager new interns, life at the hospital sizzles with more emotion, excitement, and heartbreak than ever before.

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Grey's Anatomy Season 4 release schedule

Grey's Anatomy Season 4 episode release dates
Episode Release date

1. A Change Is Gonna Come

Entering their first year as residents, Meredith Grey, Cristina Yang, Izzie Stevens and Alex Karev now have interns of their own to mentor. Among the new interns are George, forced to repeat his internship after failing his exams, and Lexie Grey, Meredith's half-sister. Another two new interns will be introduced in this season premiere. And they'll have their hands full when a three-car accident sends multiple casualties pouring into Seattle Grace. Some of the doctors need to deal with new stressed out interns. A young boy brings his bleeding deer to the hospital in the hope a doctor will save her.

Thursday · 19 years ago

2. Love/Addiction

A patient is in the hospital because they fell asleep in a hazardous situation. A patient's home laboratory blew up in an apartment building and the victims flood the hospital. Alex investigates the cause of the incident by talking to a really old guy who lived in the building. Jane Burke shows up to deal with what her son left behind. Lexie tries to talk to Meredith. Callie is overwhelmed by her new position while Bailey is searching for things to do.

Thursday · 19 years ago

3. Let the Truth Sting

The doctors meet the world's oldest intern. Marcy brings in her son Henry because she finds his change in behavior suspicious. A patient named Connie may lose her vocal chords unless Mark and Richard can perform a radical new surgery. George impresses the other interns at work but at home he is trying to deal with his guilt about having sex with Izzie.

Thursday · 19 years ago

4. The Heart of the Matter

A face familiar to one of the year-twos shows up and dredges up issues that were never really dealt with. A teen soccer player needs counseling because of his father and surgery for an injury he sustained while playing the game. Another patient's, named Courtney, finds out that her cancer is back.

Thursday · 19 years ago

5. Haunt You Every Day

It's Halloween at Seattle Grace! There may be jokes, pranks, and/or scare tactics. Some of the women form a club based on an experience they all share. A man volunteers for what most of the doctors believe is an unnecessary surgery. One of the patients is in the hospital because they tried to carve a pumpkin in an unconventional manner.

Thursday · 19 years ago

6. Kung Fu Fighting

A patient comes to the ER with a dream and a condition which may prevent him form realizing it. Two patients are competing to win something big. One of them convinces an intern to take their place.

Thursday · 19 years ago

7. Physical Attraction, Chemical Reaction

Izzie and George's new-founded relationship results in them having bad sex. Callie's Chief Resident position is taken away from her, and Bailey is the humble replacement. Meredith can barely handle it with Lexie anymore.

Thursday · 19 years ago

8. Forever Young

There has been a bus crash and the patients are in the ER. Meredith and Derek's relationship gets more complicated when he dates a fellow doctor. Meredith's dad goes to visit her at the hospital.

Thursday · 18 years ago

9. Crash Into Me (1)

An ambulance crash endangers the lives of the paramedics involved, as Meredith and the Chief work on-site to save them, Bailey treats a patient who refuses her help, and Ava returns for Alex and meets his other girlfriend in the process.

Thursday · 18 years ago

10. Crash Into Me (2) Mid-season finale

Meredith works furiously to save a paramedic trapped in an ambulance; Lexie holds the life of a patient in her hands; Derek must rely on a nurse to save a patient; Bailey struggles to balance her personal life with her work.

Thursday · 18 years ago

11. Lay Your Hands on Me

George has a surprise visitor. Bailey's family is falling apart. Derek sorts through what kissing Rose means. Meredith discovers something that doesn't inspire hope or happiness in her. Alex treats a faith healer.

Thursday · 18 years ago

12. Where The Wild Things Are

Time has passed but not much has changed. Sexual angst still runs rampant in the halls of Seattle Grace. Derek and Rose have been dating and Meredith has noticed the activities of her current off-again ex-boyfriend. The doctor's are in the midst of a competition.

Thursday · 18 years ago

13. Piece of My Heart

Addison visits Seattle Grace because they need skills that only she has. Rebecca/Ava returns with news for Alex. Meredith and Derek's clinical trial experiences one or two developments.

Thursday · 18 years ago

14. The Becoming

The clinical trial continues to make progress. The anti-McSteamy club creates new initiatives but that isn't enough to stop one woman from spending time with him. Christina is affected by Burke's career developments.

Thursday · 18 years ago

15. Losing My Mind

Dr. Wyatt refuses to let Meredith give up on therapy. Alex learns something else about Rebecca. The Chief wants Erica to perform a daring surgery. Christina continues to act strangely.

Thursday · 18 years ago

16. Freedom Finale

A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.

Thursday · 18 years ago

17. Freedom (2) Finale

A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.

Thursday · 18 years ago

Grey's Anatomy Season 4 guest stars

  • Kate Walsh

    Kate Walsh

    Addison Montgomery

  • Brooke Smith

    Brooke Smith

    Erica Hahn

  • Jurnee Smollett-Bell

    Jurnee Smollett-Bell

    Beth Monroe

  • Diahann Carroll

    Diahann Carroll

    Jane Burke

  • Loretta Devine

    Loretta Devine

    Adele Webber

  • Dylan Minnette

    Dylan Minnette

    Ryan

  • Jeff Perry

    Jeff Perry

    Thatcher Grey

  • Clea DuVall

    Clea DuVall

    Jennifer Robinson

  • Cress Williams

    Cress Williams

    Tucker Jones

  • David Burke

    David Burke

    Don

  • Theo Rossi

    Theo Rossi

    Stan Giamatti

  • Mac Brandt

    Mac Brandt

    Paramedic

  • Ron Melendez

    Ron Melendez

    Will

  • Patricia Bethune

    Patricia Bethune

    Nurse Ginger

  • Jeremy Rabb

    Jeremy Rabb

    Resident

  • Maile Flanagan

    Maile Flanagan

    Tech

Grey's Anatomy Season 4 FAQ

When does Grey's Anatomy Season 4 come out?

Grey's Anatomy Season 4 premiered Thursday, September 27, 2007 on ABC.

How many episodes are in Grey's Anatomy Season 4?

Grey's Anatomy Season 4 has 17 episodes.

Are new episodes of Grey's Anatomy Season 4 released weekly?

New episodes are released weekly.

When is the Grey's Anatomy Season 4 finale?

The Grey's Anatomy Season 4 finale (Episode 16) aired Thursday, May 22, 2008.

How do I get notified when new Grey's Anatomy Season 4 episodes are released?

Download the Streambay app and follow Grey's Anatomy. You'll get a push notification the moment each new episode is out.

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