Paul O'Grady's Little Heroes

In the final episode, Paul meets a young girl suffering from a very rare bone infection, and is on hand to keep her spirits high as she begins her recovery. Paul also meets four-year-old Rosey, who is coming out of the hospital after her 17th operation, before visiting 14-month-old baby Amelie, who has been living in the hospital since she was born.

Paul first meets three-year-old Angel, who is a regular visitor to Eagle Ward, Great Ormond Street Hospital's kidney centre, as she needs dialysis while she waits for a new kidney. He also meets 11-year-old George, who had life-saving open heart surgery at GOSH when he was just eight, and since then comes back twice a year for a series of critical cardiology tests to find out whether his condition has deteriorated.

Paul meets 13-year-old Amelie, who has been coming to the hospital since she was a baby with a very rare case of juvenile idiopathic arthritis. Meanwhile, Paul also meets eight-month-old Alexander, who was born profoundly deaf, and three-year-old Esme, who has a complex heart condition which means she has been receiving treatment in the hospital since she was 11 months old.

Paul meets 11-year-old patient Fazeel, who suffers from a rare condition known as EB, which affects just 5000 people in the UK and currently has no cure. Fazeel's condition means he has delicate, painful skin and also needs regular eye checks to look for damage or blistering inside the eye.

Paul joins eight-year-old patient Lily for a scoot around the hospital corridors. Lily was rushed to GOSH three months earlier with severe pain in her thigh. After a week of tests she was diagnosed with a rare and aggressive form of leukaemia.

Paul meets 13-year-old Mackenzie, who was born with microtia, a condition that meant his left ear was underdeveloped. He also meets brother and sister Emily and Luke, who were both born with cystic fibrosis, and gutsy nine-year-old Lara who has a blood disease that has affected her since she was a baby.

Paul meets charming four-year-old Lucy, who has travelled down from Glasgow for the latest check-up to monitor her pulmonary hypertension - a high blood pressure condition that affects the lungs. He also meets remarkable 13-year-old Connor, who is on the isolation ward as he prepares for a bone marrow transplant to help treat leukaemia. As Connor needs to live in a totally sterile environment, Paul can only speak to him through a window.

Paul meets 13-year-old Noah, who has checked into the neurology ward ahead of an operation to correct a structural defect of the skull. The youngster needs to overcome his anxiety, however, so Paul joins him on a fun tour aimed at demystifying surgical theatres. Other children include seven-year-old Oliver, a long-term patient who is struggling to walk after being struck down by arthritis, and 17-year-old Rue, who has lost much of her sight.

Paul meets energetic five-year-old Cora, who has cerebral palsy. To try to improve her co-ordination and muscle control, Cora is having Botox injections in her leg as part of a pioneering research trial. The presenter also chats to 10-year-old George, who is at the hospital for the latest round of laser surgery to lessen his facial birthmarks, and hears about three-month-old Oliver, who was born with a cleft lip.

Paul hears the story of six-year-old Noah, who was born with a genetic disorder that affects the body's organs and has been referred to Great Ormond Street for the removal of his kidney, which stopped working a long time ago. The presenter also meets a couple of two-year-olds - Lucas, who has a detached retina and needs laser surgery on his eye, and Taylor-Rose, who has accidentally swallowed a watch battery.

Paul meets 13-year-old Lola, who has been in hospital for four weeks after being diagnosed with Juvenile Dermatomyositis, which has caused inflammation of her muscles and skin. When Paul meets Lola her muscles are so weak she can't walk, but her mum explains that just six weeks earlier she had been fine. The condition affects one in a million people and Lola needs physiotherapy to help her. Also in the programme, Paul meets ten-year-old Oscar, who has Tourette's.

Paul meets five-year-old Daniel, who has been in the hospital for a month unable to walk properly after banging his knee whilst playing at home. Just after his accident, Daniel began struggling to walk and he was diagnosed with a rare type of arthritis.