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Best Medicine

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S2 E7 · Can't Stop the Healing

· in 2 days

About Best Medicine

Best Medicine is a comedy and drama TV series that premiered on FOX on January 4, 2026. It has 2 seasons and 17 episodes so far and is still airing new episodes. The latest episode, Season 2 Episode 6 "Love Is a Battlefield", aired on October 27, 2026. The next episode, Season 2 Episode 7 "Can't Stop the Healing", airs on Tuesday, November 10, 2026.

Martin Best is a brilliant surgeon who abruptly leaves his illustrious career in Boston to become the general practitioner in a quaint East Coast fishing village where he spent summers as a child. Unfortunately, Martin's blunt and borderline rude bedside manner rubs the quirky, needy locals the wrong way, and he quickly alienates the town, even though he's all they’ve got.

  • Comedy
  • Drama

Last updated

Episodes

17 episodes · 2 seasons

Best Medicine Season 3 hasn’t been dated yet. See what we know. Release date →

Season 1

2026 · 13 episodes · Last episode: 7 months ago

Best Medicine Season 1 release dates →
  1. Best Medicine S1 E13 still E13

    13. Norway No How

    Finale

    As the furious people of Port Wenn discover the truth about their deal with their Norwegian sister city, Martin must toggle between the potential revelation of his blood phobia, a startling baby delivery and the arrival of his amorous ex. Also, Louisa receives some thought-provoking medical results and Al and Elaine must navigate their uncertain future.

  2. Best Medicine S1 E12 still E12

    12. A Tale of Two Sister Cities

    Martin is skeptical when Port Wenn welcomes an extremely friendly delegation from their sister city in Norway and Louisa visits a specialist who just happens to be Martin's ex. Also, Greg believes that he is pooping little men and Mark exhibits troubling symptoms that warrant an intervention.

  3. Best Medicine S1 E11 still E11

    11. Mind Your Own Buboes

    Port Wenn goes on lockdown when a patient with fleas sparks fears of a plague outbreak; Martin must deal with the town gossip when it revolves around him and Louisa; Aunt Sarah feels betrayed by Greg and George; Louisa has an epiphany.

  4. Best Medicine S1 E10 still E10

    10. Port Wenn-ings and a Funeral

    After Martin invites Louisa to watch the annual bird migration over Port Wenn, he treats an elderly woman whose hallucinations lead to dire consequences. Meanwhile, Aunt Sarah fumes after the reading of a will leaves her nothing and Martin must perform an emergency procedure on his young friend.

  5. Best Medicine S1 E9 still E9

    9. Doc Martin

    When Martin's parents make a surprise visit, Martin suspects that his father is experiencing a serious health condition; Louisa is made acting principal; Martin and Robert must operate together on Mark.

  6. Best Medicine S1 E8 still E8

    8. The Bogfather

    Port Wenn eagerly goes into high alert when a corpse is found in the town's bog and Martin's autopsy reveals that he was murdered. Meanwhile, Martin's solo investigation trek leads him to startling discovery about himself and the new neighborhood watch turns into a gossip-seeking mission.

  7. Best Medicine S1 E7 still E7

    7. There Might Be Blood

    When Port Wenn puts on their annual 'Blood Factory,' celebrating the gory horror novel set there, Martin must contain his secret debilitating blood phobia when Louisa gets seriously ill and needs his help. Meanwhile, the town is all atwitter when the novel's author is rumored to be making a surprise visit to the event.

  8. Best Medicine S1 E6 still E6

    6. Eyewitness Blues

    On the eve of Port Wenn's annual blueberry festival, Martin treats a local man who has apparently become blue from eating too many blueberries; Martin is disturbed by Aunt Sarah's lack of attention to her health.

  9. Best Medicine S1 E5 still E5

    5. Hello Darkness, My Port Wenn

    While conducting a wellness check on the agoraphobic recluse who controls the town power grid, Martin's brusque bedside manner ultimately causes a massive town black out; as the townspeople fight for electricity, Martin befriends a young boy who reminds him of himself; Louisa and Mark share a romantic moment in the dark.

  10. Best Medicine S1 E4 still E4

    4. All the World's Ablaze

    Port Wenn's favorite hunky wilderness survival instructor goes missing after Martin deduces that he desperately needs medical help. Also, the locals are furious with Martin after he calls the health inspector on The Salty Breeze suspecting food poisoning and Elaine decides to skip her mother's wedding to the school principal.

  11. Best Medicine S1 E3 still E3

    3. Take Me Out of the Ballgame

    On the eve of Port Wenn High School's baseball team's playoff game, the town is furious with Martin when he accidentally breaks the arm of their star player, who happens to be the son of his high school bully. However, Martin suspects the boy has a more serious condition. Meanwhile, Elaine moves into Martin's waiting room after fighting with her mom, Aunt Sarah rivals with a fan of the opposing team, and Louisa makes a conscious effort to make some female friends.

  12. Best Medicine S1 E2 still E2

    2. Bean There Done That

    After Martin comes face to face with his childhood bully and diagnoses a potentially contagious illness, he is forced to cancel Port Wenn's monthly baked bean supper, angering everyone in the town. Also, Louisa observes Mark getting friendly with her teaching assistant, while Elaine steps in to help Martin in an unexpected, but very much needed, way.

  13. Best Medicine S1 E1 still E1

    1. Docked

    Brilliant and brusque renowned surgeon Martin Best leaves his lucrative career in Boston to become the general practitioner in the small seaside village of Port Wenn, Maine. One local teacher, Louisa Gavin questions his harsh demeanor, while Martin quickly gets annoyed by the antics of its town locals, all while hiding his debilitating aversion to blood.

Season 2

2026 · 7 episodes · Last episode: 1 week ago

Best Medicine Season 2 release dates →
  1. E5

    5. Hare Today, Gone Tomorrow

    When the wife of a traveling magician duo dies at the Salty Breeze, Martin must help the husband who is unable to grasp that she is gone. Also, Eden finds a letter Martin wrote to Louisa thinking it was for her and Martin gets a new medical monitor who has an instant connection to Louisa.

  2. Best Medicine S2 E4 still E4

    4. No Place Like Om

    As Martin desperately tries to leave Port Wenn to meet Eden in Boston for the weekend, he must first investigate the extremely strange behavior of three patients who have all recently visited a meditation retreat. Also, Mark is affected by the high school's graduation and Sarah's first guest in her rented spare room is none other than ex-paramour Eddie McCroy.

  3. Best Medicine S2 E3 still E3

    3. Crate Expectations

    The citizens of Port Wenn get competitive during their annual floating crate race; Martin tries to give important medical advice when three men have positive pregnancy tests; former record-holder Sarah coaches Peter in the art of crate racing.

  4. Best Medicine S2 E2 still E2

    2. Breakin' In Is Hard to Do

    When the Port Wenn pharmacy is robbed, including Louisa’s critical time-sensitive medicine, Martin deduces that the culprit desperately needs his help. Meanwhile, Greg and George clash with a rival food truck owner, Sarah tries to bond with Eden, and Martin is on the receiving end of a special brand of Port Wenn affection.

  5. Best Medicine S2 E1 still E1

    While Martin continues to struggle with his blood phobia, a mermaid washes ashore in Port Wenn to the amazement of everyone in town. Meanwhile, Judith, a well-meaning townsperson (guest star Andrea Martin), creates havoc while on prescribed oxygen, Louisa continues to see Martin's girlfriend Eden for medical guidance and Greg and George's success from the seas urchin boom take its toll on the both of them.

Cast & crew

Created by Liz Tuccillo

  • Stephen Spinella

    Stephen Spinella

    Greg Garrison

  • Jason Veasey

    Jason Veasey

    George Brady

  • Carter Shimp

    Carter Shimp

    Al Large

  • John DiMaggio

    John DiMaggio

    Bert Large

  • Clea Lewis

    Clea Lewis

    Sally Mylow

  • Michael Potts

    Michael Potts

    Gilbert Carlisle

  • Didi Conn

    Didi Conn

    Geneva

  • Ben Lewis Doherty

    Ben Lewis Doherty

    Peter Cronk

  • Wendy Makkena

    Wendy Makkena

    Susan Carlisle

  • Adrian Enscoe

    Adrian Enscoe

    Doug

  • Martin Clunes

    Martin Clunes

    Dr. Robert Best

  • Heléne Yorke

    Heléne Yorke

    Savannah Michaud

  • Eliza Coupe

    Eliza Coupe

    Dr. Eden Montgomery

  • Alexandra Sica

    Harley

  • Leah Janae Thomas

    Amelia

  • Josh Hoon Lee

    Liam

Best Medicine FAQ

When is the next episode of Best Medicine?

The next episode of Best Medicine, Season 2 Episode 7 "Can't Stop the Healing", airs on Tuesday, November 10, 2026. Get the Streambay app to be notified the moment it's out.

When did the latest episode of Best Medicine come out?

The most recent episode of Best Medicine, Season 2 Episode 6 "Love Is a Battlefield", aired on October 27, 2026.

How many seasons of Best Medicine are there?

Best Medicine has 2 seasons with 17 episodes in total.

When did Best Medicine first air?

Best Medicine first aired on FOX on January 4, 2026.

How do I get notified when new episodes of Best Medicine are released?

Download the Streambay app, follow Best Medicine, and you'll get a push notification the moment each new episode is released.

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